Meet Polyendocrine Metabolic-Ovarian Syndrome (PMOS), formerly Polycystic Ovary Syndrome (PCOS)

Polyendocrine Metabolic-Ovarian Syndrome (PMOS) formerly known as Polycystic Ovary Syndrome (PCOS) is a multisystem-condition characterized by hormonal and metabolic dysfunction. You might ask, why the name change?

The recently changed name more accurately reflects the condition. While polycystic ovaries are frequently a feature of the condition, they are just a small part of a more global story.

Individuals with PMOS experience:

• high levels of androgen hormones,
• insulin resistance, and
• frequently, ovarian cysts.

These all contribute to alterations in overall metabolic functioning, and may lead to:

• cardiovascular issues,
• challenges with fertility, and
• weight gain.

Managing PMOS often takes a multidisciplinary approach, regular exercise, and medication. Moderate-intensity aerobic activity and strength training are beneficial for all of us. And they are particularly beneficial for individuals with PMOS to help regulate menstrual cycles and reduce insulin resistance. Experts recommend both moderate-intensity aerobic activity and strength training to improve metabolic functioning.

In addition, doctors may recommend a variety of medications depending on a patients’ goals. Some common medications prescribed are:

• GLP1s– a recent addition to the list of PMOS treatment options, GLP1s can serve to improve insulin resistance, reduce inflammation, and help patients maintain a healthy weight.
• Metformin– lowers blood sugar and improves insulin resistance.
• Oral Birth Control– can be used to alter the hormonal profile to reduce androgen levels. If you are trying to conceive, other medications may be considered to trigger ovulation.
• Spironolactone– manages excess androgens helping reduce unwanted hair growth, acne and hair thinning.

Pelvic floor PT can be a valuable component of a PMOS management plan. Many people who have PMOS experience pelvic pain, bowel, bladder and/or sexual dysfunction.

While pelvic floor PT can not change the metabolic profile of the body, it can help control muscle tension that may contribute to pain in the pelvic floor, abdomen, back and hips. Additionally, optimizing strength, endurance, and coordination of the pelvic floor can help address bowel, bladder or sexual dysfunction.

With a multidisciplinary care team and a comprehensive management plan, individuals with PMOS can manage their condition, resulting in a significant reduction in symptoms and pain throughout the body.